Publications

1. Duffy, M.R., Bradshaw, A.C., Parker, A.L., McVey, J.H. and Baker, A.H. (2011) A cluster of basic amino acids in the factor X serine protease mediate surface attachment of adenovirus:FX complexes. J. Virol., in press.
2. Rahim, A.A., Wong, A.M-S., Ahmadi, S., Hoefer, K., Buckley, S.M.K., Hughes, D.A., Nathwani, A.N., Baker, A.H., McVey, J.H., Cooper, J.D. and Waddington, S.N. (2011) In utero administrationof Ad5 and AAV pseudotypes to the fetal brain leads to efficient, widespread and long-term gene expression. Gene Therapy, in press.
3. Goodeve, A. C., Reitsma, P. and McVey, J. H., on behalf of the Working Group on Nomenclature of the Scientific and Standardisation Committee of the International Society on Thrombosis and Haemostasis (2011). Scientific and standardisation committee communication: a standard system for nomenclature of genetic variants in haemostasis. Journal of Thrombosis and Haemostasis 9, 852-855.
4. Ward, N. J., Buckley, S. M. K., Waddington, S. N., VandenDriessche, T., Chuah, M. K. L., Nathwani, A. C., McIntosh, J., Tuddenham, E. G. D., Kinnon, C., Thrasher, A. J. and McVey, J. H. (2011). Codon optimisation of human factor VIII cDNAs leads to high level expression. Blood 117, 798-807.
   [ ABSTRACT ] [ SUPPLEMENTAL FIGURE ]
5. Alba, R., Bradshaw, A. C., Coughlan, L., Denby, L., McDonald, R. A., Waddington, S. N., Buckley, S. M. K., Greig, J. A., Parker, A. L., Miller, A. M., Wang, H., Lieber, A., van Rooijen, N., McVey, J. H., Nicklin, S. A. and Baker, A. H. (2010). Biodistribution and retargeting of FX-binding ablated adenovirus serotype 5 vectors. Blood 116, 2656-2654.
   [ ABSTRACT ]
6. McVey, J. H. (2010). O tissue factor, where art thou tissue factor. Blood 116, 676-677.
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7. Alba, R., Bradshaw, A. C., Parker, A. L., Bhella, D., Waddington, S. N., Nicklin, S. A., van Rooijen, N., Custers, J., Goudsmit, J., Barouch, D. H., McVey, J. H. and Baker, A. H. (2009). Identification of coagulation factor (F)X binding sites on the adenovirus serotype 5 hexon: effect of mutagenesis on FX interactions and gene transfer. Blood 114, 965-971.
   [ ABSTRACT ] [ EDITORIAL COMMENT ]
8. Greig, J. A., Buckley, S. M. K., Waddington, S. N., Parker, A. L., Bhella, D., Pink, R., Rahim, A. A., Morita, T., Nicklin, S. A., McVey, J. H. and Baker, A. H. (2009). Influence of coagulation factor X on in vitro and in vivo gene delivery by adenovirus (Ad) 5, Ad35 and chimeric Ad5/Ad35 vectors. Molecular Therapy 17, 1683-1691.
   [ COVER ] [ ABSTRACT ] [ FULL TEXT ]
9. Lenaerts, L., McVey, J. H., Baker, A. H., Denby, L., Nicklin, S., Verbeken, E. and Naesens, L. (2009). Mouse adenovirus type 1 and human adenovirus type 5 differ in endothelial cell tropism and liver targeting. The Journal of Gene Medicine 11, 119-127.
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10. Maroney, S. A., Ferrel, J. P., Pan, S., White, T. A., Simari, R. D., McVey, J. H. and Mast, A. E. (2009). Temporal expression of alternatively spliced forms of tissue factor pathway inhibitor in mice. Journal of Thrombosis and Haemostasis 7, 1106-1113.
    [ ABSTRACT ]
11. McVey, J. H. (2009). FVIIa gene delivery: potential treatment for hemophilia? Blood 113, 3649-3650.
    [ COVER ] [ FULL TEXT ]
12. Parker, A. L., Waddington, S. N., Buckley, S. M. K., Custers, J., Havenga, M. J. E., van Rooijen, N., Goudsmit, J., McVey, J. H., Nicklin, S. A. and Baker, A. H. (2009). Effect of neutralising sera on factor X-mediated adenoviral serotype 5 gene transfer.
    Journal of Virology 83, 479-483.
    [ ABSTRACT ] [ FULL TEXT ]
13. Chen, D., Abrahams, J. M., Smith, L. M., McVey, J. H., Lechler, R. I. and Dorling A. (2008). Regenerative repair after endoluminal injury in mice with specific antagonism of protease activated receptors on CD34⁺ vascular progenitors. Blood 11, 4155-4164.
    [ ABSTRACT ] [ FULL TEXT ]
14. Chen, D., Carpenter, A., Abrahams, J., Chambers, R. C., Lechler, R. I., McVey, J. H. and Dorling, A. (2008). Protease-activated receptor 1 activation is necessary for monocyte chemoattractant protein 1-dependent leukocyte recruitment in vivo. The Journal of Experimental Medicine 8, 1739-1746.
    [ ABSTRACT ] [ FULL TEXT ]
15. Lin, C. C., Chen, D., McVey, J. H., Cooper, D. K. C. and Dorling, A. (2008). Expression of tissue factor and initiation of clotting by human platelets and monocytes after incubation with porcine endothelial cells. Transplantation 86, 702-709.
    [ ABSTRACT ]
16. Waddington, S. N., McVey, J. H., Bhella, D., Parker, A. L., Barker, K., Atoda, H., Pink, R., Buckley, S. M. K., Greig, J. A., Denby, L., Custers, J., Morita, T., Francischetti, I. M. B., Monteiro, R. Q., Barouch, D. H., van Rooijen, N., Napoli, C., Havenga, M. J. E., Nicklin, S. A. and Baker, A. H. (2008). Adenovirus serotype 5 hexon mediates liver gene transfer. Cell 132, 397-409.
    [ ABSTRACT ]
17. Wang, H., Liu, Y., Li, Z., Tuve, S., Stone, D., Kalyushniy, O., Shayakhmetov, D., Verlinde, C. L. M., Stehle, T., McVey, J., Baker, A., Peng, K.-W., Roffler, S. and Lieber, A. (2008). In vitro and in vivo properties of adenovirus vectors with increased affinity to CD46. Journal of Virology 82, 10567-10579.
    [ ABSTRACT ]
18. White, K., Büning, H., Kritz, A., Janicki, H., McVey, J., Perabo, L., Murphy, G., Odenthal, M., Work, L. M., Hallek, M., Nicklin, S. A. and Baker, A. H. (2008). Engineering adeno-associated virus 2 vectors for targeted gene delivery to atherosclerotic lesions. Gene Therapy 15, 443-451.
    [ ABSTRACT ]
19. Baker, A. H., Mcvey, J. H., Waddington, S. N., Di Paolo, N. C. and Shayakhmetov, D. M. (2007). The influence of blood on in vivo adenovirus bio-distribution and transduction. Molecular Therapy 15, 1410-1416.
    [ ABSTRACT ]
20. Bolton-Maggs, P. H. B., Hay, C. R. M., Shanks, D., Mitchell, M. J. and McVey, J. H. (2007). The importance of tissue factor source in the management of Factor VII deficiency. Thrombosis and Haemostasis 97, 151-152.
21. Denby, L., Work, L. M., Von Seggern, D. J., Wu, E., McVey, J. H., Nicklin, S. A. and Baker, A. H. (2007). Development of renal-targeted vectors through combined in vivo phage display and caspid engineering of adenoviral fibers from serotype 19p. Molecular Therapy 15, 1647-1654.
    [ ABSTRACT ]
22. Kritz, A. B., Nicol, C. G., Dishart, K. L., Nelson, R., Holbeck, S., Von Seggern, D. J., Work, L. M., McVey, J. H., Nicklin, S. A. and Baker, A. H. (2007). Adenovirus 5 fibers mutated at the KKTK putative HSPG binding site fail to retarget when engineered with targeting peptides in the HI loop. Molecular Therapy 15, 741-749.
    [ ABSTRACT ]
23. Parker, A. L., McVey, J. H., Doctor, J. H., Lopez-Franco, O., Waddington, S. N., Havenga, M. J. E., Nicklin, S. A. and Baker, A. H. (2007). Influence of coagulation factor zymogens on the infectivity of adenoviruses pseudotyped with fibers from subgroup D. Journal of Virology 81, 3627-3631.
    [ ABSTRACT ]
24. Shrivastava, S., McVey, J. H. and Dorling, A. (2007). The interface between coagulation and immunity. American Journal of Transplantation 7, 499-506.
    [ ABSTRACT ]
25. Waddington, S. N., Parker, A. L., Havenga, M., Nicklin, S. A., Buckley, S. M. K., McVey, J. H. and Baker, A. H. (2007). Targeting of adenovirus serotype 5 (Ad5) and 5/47 pseudotyped vectors in vivo: a fundamental involvement of coagulation factors and redundancy of CAR binding by Ad5. Journal of Virology 81, 9568-9672.
    [ ABSTRACT ]
26. Chen, D., Weber, M., Shiels, P. G., Dong, R., Webster, Z., McVey, J. H., Kemball-Cook, G., Tuddenham, E. G. D., Lechler, R. I. and Dorling, A. (2006). Postinjury vascular intimal hyperplasia in mice is completely inhibited by CD34+ bone marrow-derived progentor cells expressing membrane-tethered anticoagulant fusion proteins. Journal of Thrombosis and Haemostasis 4, 2191-2198.
    [ ABSTRACT ]
27. Gomez, K. and McVey, J. H. (2006). Tissue factor initiated blood coagulation. Frontiers in Bioscience 11, 1349-1359.
    [ ABSTRACT ]
28. Parker, A. L., Waddington, S. N., Nicol, C. G., Shayakhmetov, D. M., Buckley, S. M., Denby, L., Kemball-Cook, G., Ni, S., Lieber, A., McVey, J. H., Nicklin, S. A. and Baker, A. H. (2006). Multiple vitamin K-dependent coagulation zymogens promote adenovirus-mediated gene delivery to hepatocytes. Blood 108, 2554-2561.
    [ ABSTRACT ]
29. Albrecht, C., McVey, J. H., Elliott, J. I., Sardini, A., Kasza, I., Mumford, A. D., Naoumova, R. P., Tuddenham, E. G., Szabo, K. and Higgins, C. F. (2005). A novel missense mutation in ABCA1 results in altered protein trafficking and reduced phosphatidylserine translocation in a patient with Scott syndrome. Blood 106, 542-549.
    [ ABSTRACT ]
30. Elliott, J. I., McVey, J. H. and Higgins, C. F. (2005). The P2X₇ receptor is a candidate product of murine and human lupus susceptibility loci: a hypothesis and comparison of murine allelic products. Arthritis Research & Therapy 7, R468-R475.
    [ ABSTRACT ] [ FULL TEXT ]
31. Gomez, K., McVey, J. H. and Tuddenham, E. (2005). Inhibition of coagulation by macromolecular complexes. Haematologica 90, 1570-1576.
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32. McVey, J. H., Lal, K., Imanaka, Y., Kemball-Cook, G., Bolton-Maggs, P. H. B. and Tuddenham, E. G. D. (2005). Characterisation of blood coagulation factor XI T475I. Thrombosis and Haemostasis 93, 1082-1088.
    [ ABSTRACT ]
33. Mumford, A. D., Chen, D., Dorling, A., Kemball-Cook, G. and McVey, J. H. (2005). Generation of a polyclonal rabbit anti-mouse tissue factor antibody by nucleic acid immunisation. Thrombosis and Haemostasis 93, 160-164.
    [ ABSTRACT ]
34. Chen, D., Giannopoulos, K., Shiels, P. G., Webster, Z., McVey, J. H., Kemball-Cook, G., Tuddenham, E., Moore, M., Lechler, R. and Dorling, A. (2004). Inhibition of intravascular thrombosis in murine endotoxaemia by targeted expression of hirudin and tissue factor pathway inhibitor analogs to activated endothelium. Blood 104, 1344-1349.
    [ ABSTRACT ] [ FULL TEXT ]
35. Chen, D., Weber, M., McVey, J. H., Kemball-Cook, G., Tuddenham, E. G. D., Lechler, R. I. and Dorling, A. (2004). Complete inhibition of acute humoral rejection using regulated expression of membrane-tethered anticoagulants on xenograft endothelium. American Journal of Transplantation 4, 1958-1963.
    [ ABSTRACT ] [ FULL TEXT ]
36. Elliott, J. I., Mumford, A. D., Albrecht, C., Collins, P. W., Giddings, J. C., Higgins, C. F., Tuddenham, E. G. D. and McVey, J. H. (2004). Characterisation of lymphocyte responses to Ca²⁺ in Scott syndrome. Thrombosis and Haemostasis 91, 412-415.
37. Gomez, K., Laffan, M. A., Kemball-Cook, G., Pasi, J., Layton, M., Singer, J. D., Tuddenham, E. G. D. and McVey J. H. (2004). Two novel mutations in severe factor VII deficiency. British Journal of Haematology 126, 105-110.
    [ ABSTRACT ]
38. Mumford, A. D. and McVey, J. H. (2004). Tissue factors in the myocardium: Evidence of roles in haemostasis and inflammation. Disease Markers 20, 353-358.
    [ ABSTRACT ]
39. Steen, M., Norstrøm, E. A., Tholander, A.-L., Bolton-Maggs, P. H. B., Mumford, A., McVey, J. H., Tuddenham, E. G. and Dahlbäck, B. (2004). Functional characterization of Factor V-Ile359Thr: a novel mutation associated with thrombosis. Blood 103, 3381-3387.
    [ ABSTRACT ] [ FULL TEXT ]
40. Takács, K., Du Roure, C., Nabarro, S., Dillon, N., McVey, J. H., Webster, Z., MacNeil, A., Bartók, I., Higgins, C., Gray, D., Merkenschlager, M. and Fisher, A. G. (2004). The regulated long-term delivery of therapeutic proteins by using antigen-specific B lymphocytes. Proceedings of the National Academy of Sciences of the United States of America 101, 16298-16303.
    [ ABSTRACT ]
41. Bachli, E. B., Pech, C. M., Johnson, K. M., Johnson, D. J. D., Tuddenahm, E. G. D. and McVey, J. H. (2003). Factor Xa and thrombin, but not factor VIIa, elicit specific cellular responses in dermal fibroblasts. Journal of Thrombosis and Haemostasis 1, 1935-1944.
    [ ABSTRACT ] [ FULL TEXT ]
42. David, D., Santos, I. M. A., Johnson, K., Tuddenham, E. G. D. and McVey, J. H. (2003). Analysis of the consequences of premature termination codons within factor VIII coding sequences. Journal of Thrombosis and Haemostasis 1, 139-146.
    [ ABSTRACT ] [ FULL TEXT ]
43. Davidson, C. J., Hirt, R. P., Lal, K., Snell, P., Elgar, G., Tuddenham, E. G. D. and McVey, J. H. (2003). Molecular evolution of the vertebrate blood coagulation network. Thrombosis and Haemostasis 89, 420-428.
    [ ABSTRACT ]
44. Davidson, C. J., Tuddenahm, E. G. and McVey, J. H. (2003). 450 million years of hemostasis. Journal of Thrombosis and Haemostasis 1, 1487-1494.
    [ ABSTRACT ] [ FULL TEXT ]
45. McVey, J. (2003). Your bleeding heart: lessons from low tissue factor expression in mice. Trends in Pharmacological Science 24, 269-272.
    [ ABSTRACT ]
46. Mumford, A. D., McVey, J. H., Morse, C. V., Gomez, K., Steen, M., Norstrom, E. A., Tuddenham, E. G. D., Dahlrack, B. and Bolton-Maggs, P. H. B. (2003). Factor V 1359T: a novel mutation associated with thrombosis and resistance to activated protein C. British Journal of Haematology 123, 496-501.
    [ ABSTRACT ]
47. Zhang, B., Cunningham, M. A., Nichols, W. C., Bernat, J. A., Seligsohn, U., Pipe, S. W., McVey, J. H., Schulte-Overberg, U., de Bosch, N. B., Ruiz-Saez, A., White, G. C., Tuddenham, E. G. D., Kaufman, R. J. and Ginsburg, D. (2003). Bleeding due to disruption of a cargo-specific ER-to-Golgi transport complex. Nature Genetics 34, 220-225.
    [ ABSTRACT ]
48. Mumford, A. D., Laffan, M., O'Donnell, J., McVey, J. H., Johnson, D. J. D., Manning, R. A. and Kemball-Cook, G. (2002). A Tyr346 → Cys substitution in the interdomain acidic region a1 of factor VIII in an individual with factor VIII:C assay discrepancy. British Journal of Haematology 118, 589-594.
    [ ABSTRACT ] [ FULL TEXT ]
49. Brown, P. J., Gill, A. C., Nugent, P. G., McVey, J. H. and Tomley, F. M. (2001). Domains of invasion organelle proteins from apicomplexan parasites are homologous with the Apple domains of blood coagulation factor XI and plasma pre-kallikrein and are members of the PAN module superfamily. FEBS Letters 497, 31-38.
    [ ABSTRACT ] [ FULL TEXT ]
50. Chen, D., Riesbeck, K., McVey, J. H., Kemball-Cook, G., Tuddenham, E. G. D., Lechler, R. I. and Dorling, A. (2001). Human thrombin and FXa mediate porcine endothelial cell activation; modulation by expression of TFPI-CD4 and hirudin-CD4 fusion proteins. Xenostransplantation 8, 258-265.
    [ ABSTRACT ]
51. Christian, M., Marangos, P., Mak, I., McVey, J., Barker, F., White, J. and Brosens, J. J. (2001). Interferon- modulates prolactin and tissue factor expression in differentiating human endometrial stromal cells. Endocrinology 142, 3142-3151.
    [ ABSTRACT ] [ FULL TEXT ]
52. David, D., Saenko, E. L., Santos, I. M. A., Johnson, D. J. D., Tuddenham, E. G. D., McVey, J. H. and Kemball-Cook, G. (2001). Stable recombinant expression and characterization of the two haemophilic factor VIII variants C329S (CRM^–) and G1948D (CRM^r). British Journal of Haematology 113, 604-615.
    [ ABSTRACT ]
53. McVey, J. H., Boswell, E., Mumford, A. D., Kemball-Cook, G. and Tuddenham, E. G. D. (2001). Factor VII deficiency and the FVII mutation database. Human Mutation 17, 3-17.
    [ ABSTRACT ]
54. Dorling, A., Chen, D., Riesbeck, K., McVey, J., Kemball-Cook, G., Tuddenham, E. G. and Lechler, R. I. (2000). Regulated endothelial cell expression of novel anticoagulants: a strategy for the prevention and therapy of intravascular thrombosis. Transplantation Proceedings 32, 971.
55. Millar, D. S., Kemball-Cook, G., McVey, J. H., Tuddenham, E. G., Mumford, A. D., Attock, G. B., Reverter, J. C., Lanir, N., Parapia, L. A., Reynaud, J., Meili, E., von Felton, A., Martinowitz, U., Prangnell, D. R., Krawczak, M. and Cooper, D. N. (2000). Molecular analysis of the genotype-phenotype relationship in factor VII deficiency. Human Genetics 107, 327-342.
    [ ABSTRACT ]
56. Shibata, M., Shima, M., Morichika, S., McVey, J., Tuddenham, E. G. D., Tanaka, I., Suzuki, H., Nogami, K., Minamoto, Y., Hato, T., Saenko, E. L., Scandella, D. and Yoshioka, A. (2000). An alloantibody recognizing the FVIII A1 domain in a patient with CRM reduced haemophilia A due to deletion of a large portion of the A1 domain DNA sequence. Thrombosis and Haemostasis 84, 442-448.
    [ ABSTRACT ]
57. Ventura, C., Santos, A. I. M., Tavares, A., Gago, T., Lavinha, J., McVey, J. H. and David, D. (2000). Molecular genetic analysis of factor XI deficiency: identification of five novel gene alterations and the origin of type II mutation in Portuguese families. Thrombosis and Haemostasis 84, 833-840.
    [ ABSTRACT ]
58. Chen, D., Riesbeck, K., Kemball-Cook, G., McVey, J. H., Tuddenham, E. G. D., Lechler, R. I. and Dorling, A. (1999). Inhibition of tissue factor-dependent and -independent coagulation by cell surface expression of novel anticoagulant fusion proteins. Transplantation 67, 467-474.
    [ ABSTRACT ]
59. Chen, D., Riesbeck, K., McVey, J. H., Kemball-Cook, G., Tuddenham, E. G. D., Lechler, R. I. and Dorling, A. (1999). Regulated inhibition of coagulation by porcine endothelial cells expressing P-selectin-tagged hirudin and tissue factor pathway inhibitor fusion proteins. Transplantation 68, 832-839.
    [ ABSTRACT ]
60. Houston, P., Dickson, M. C., Ludbrook, V., White, B. Schwachtgen, J.-L., McVey, J. H., Mackman, N., Reese, J. M., Gorman, D. G., Campbell, C. and Braddock, M. (1999). Fluid shear stress induction of the tissue factor promoter in vitro and in vivo is mediated by Egr-1. Arteriosclerosis, Thrombosis, and Vascular Biology 19, 281-289.
    [ ABSTRACT ] [ FULL TEXT ]
61. McVey, J. H. (1999). Tissue factor pathway. Bailleres Best Practice & Research in Clinical Haematology 12, 361-372.
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62. Neerman-Arbez, M., Johnson, K. M., Morris, M. A., McVey, J. H., Peyvandi, F., Nichols, W. C., Ginsburg, D., Rossier, C., Antonarakis, S. E. and Tuddenham, E. G. D. (1999). Molecular analysis of the ERGIC-53 gene in 35 families with combined factor V-factor deficiency. Blood 93, 2253-2260.
    [ ABSTRACT ] [ FULL TEXT ]
63. Kemball-Cook, G., Johnson, D. J. D., Takamiya, O., Banner, D. W., McVey, J. H. and Tuddenham, E. G. D. (1998). Coagulation factor VII Gln¹⁰⁰ → Arg. Amino acid substitution at the epidermal growth factor 2-protease domain interface results in severely reduced tissue factor binding and procoagulant function. The Journal of Biological Chemistry 273, 8516-8521.
    [ ABSTRACT ] [ FULL TEXT ]
64. Mansvelt, E. P. G., Laffan, M., McVey, J. H. and Tuddenham, E. G. D. (1998). Analysis of the F8 gene in individuals with high plasma factor VIII:C levels and associated venous thrombosis. Thrombosis and Haemostasis 80, 561-565.
    [ ABSTRACT ]
65. McVey, J. H., Boswell, E. J., Takamiya, O., Tamagnini, G., Valente, V., Fidalgo, T., Layton, M. and Tuddenham, E. G. D. (1998). Exclusion of the first EGF domain of factor VII by a splice site mutation causes lethal factor VII deficiency. Blood 92, 920-926.
    [ ABSTRACT ] [ FULL TEXT ]
66. Palmer, D. B., McVey, J. H., Purohit, R., Picard, J. and Dyson, P. J. (1998). Characterization of a recent retroposon insertion on mouse Chromosome 2 and localization of the cognate parental gene to Chromosome 11. Mammalian Genome 9, 103-106.
    [ ABSTRACT ]
67. Riesbeck, K., Chen, D., Kemball-Cook, G., McVey, J. H., George, A. J. T., Tuddenham, E. G. D., Dorling, A. and Lechler, R. I. (1998). Expression of hirudin fusion proteins in mamalian cells: a strategy for prevention of intravascular thrombosis. Circulation 98, 2744-2752.
    [ ABSTRACT ] [ FULL TEXT ]
68. Tuddenham, E. G. D. and McVey, J. H. (1998). The genetic basis of inhibitor development in haemophilia A. Haemophilia 4, 543-545.
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69. Morichika, S., Shima, M., Kamisue, S., Tanaka, I., Imanaka, Y., Suzuki, H., Shibata, H., Pemberton, S., Gale, K., McVey, J., Tuddenham, E. G. D. and Yoshioka, A. (1997). Factor VIII gene analysis in Japanese CRM-positive and CRM-reduced haemophilia A patients by single-strand conformation polymorphism. British Journal of Haematology 98, 901-906.
    [ ABSTRACT ]
70. Riesbeck, K., Dorling, A., Kemball-Cook, G., McVey, J. H., Jones, M., Tuddenham, E. G. and Lechler, R. I. (1997). Human tissue factor pathway inhibitor fused to CD4 binds both FXa and TF/FVIIa at the cell surface. Thrombosis and Haemostasis 78, 1488-1494.
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71. Imanaka, Y., Lal, K., Nishimura, T., Bolton-Maggs, P. H. B., Tuddenham, E. G. D. and McVey, J. H. (1995). Identification of two novel mutations in non-Jewish factor XI deficiency. British Journal of Haematology 90, 916-920.
    [ ABSTRACT ] [ FULL TEXT ]
72. Pugh, R. E., McVey, J. H., Tuddenham, E. G. and Hancock, J. F. (1995). Six point mutations that cause factor XI deficiency. Blood 85, 1509-1516.
    [ ABSTRACT ] [ FULL TEXT ]
73. Takamiya, O. T., Abe, S., Yoshioka, A., Nakajima, K., McVey, J. H. and Tuddenham, E. G. D. (1995). Factor_VIIShinjo: a dysfunctional factor VII variant homozygous for the substitution Gln for Arg at position 79. Haemostasis 25, 89-97.
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74. Kemball-Cook, G., Garner, I., Imanaka, Y., Nishimura, T., O'Brien, D. P., Tuddenham, E. G. D. and McVey, J. H. (1994). High-level production of human blood coagulation factors VII and XI using a new mammalian expression vector. Gene 139, 275-279.
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75. Kochhan, L., Lalloz, M. R., Oldenburg, J., McVey, J. H., Olek, K., Brackmann, H. H., Tuddenham, E. G. D. and Schwaab, R. (1994). Haemophilia A diagnosis by automated fluorescent DNA detection of ten factor VIII intron 13 dinucleotide repeat alleles. Blood Coagulation & Fibrinolysis 5, 497-501.
    [ ABSTRACT ]
76. Lalloz, M. R. A., Schwaab, R., McVey, J. H., Michaelides, K. and Tuddenham, E. G. D.(1994). Haemophilia A diagnosis by simultaneous analysis of two variable dinucleotide tandem repeats within the factor VIII gene. British Journal of Haematology 86, 804-809.
    [ ABSTRACT ] [ FULL TEXT ]
77. McVey, J. H. (1994). 3 Tissue factor pathway. Baillière's Clinical Haematology 7, 469-484.
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78. McVey, J. H. (1994). Staden Plus. Methods in Molecular Biology 25, 171-179.
79. Nathwani, A. C., Gale, K. M., Pemberton, K. D., Crossman, D. C., Tuddenham, E. G. D. and McVey, J. H. (1994). Efficient gene transfer into human umbilical vein endothelial cells allows functional analysis of the human tissue factor gene promoter. Bristish Journal of Haematology 88, 122-128.
    [ ABSTRACT ] [ FULL TEXT ]
80. O'Brien, D. P., Kemball-Cook, G., Hutchinson, A. M., Martin, D. M. A., Johnson, D. J. D., Byfield, P. G. H., Takamiya, O., Tuddenham, E. G. D. and McVey, J. H. (1994). Surface plasmon resonance studies of the interaction between factor VII and tissue factor. Demonstration of defective tissue factor binding in a variant FVII molecule (FVII-R79Q). Biochemistry 33, 14162-14169.
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81. Connolly, D. J., Cotterill, L. A., Hederer, R. A., Thorpe, C. J., Travers, P. J., McVey, J. H., Dyson, J. and Robinson, P. J. (1993). A cDNA clone encoding the mouse Qa-1a histocompatibility antigen and proposed structure of the putative peptide binding site. The Journal of Immunology 151, 6089-6098.
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82. McVey, J. H., Michaelides, K., Hansen, L. P., Ferguson-Smith, M., Tilghman, S., Krumlauf, R. and Tuddenham, E. G. D. (1993). A G → A substitution in an HNF I binding site in the human α-fetoprotein gene is associated with hereditary persistence of α-fetoprotein (HPAFP). Human Molecular Genetics 2, 379-384.
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83. Takamiya, O., Kemball-Cook, G., Martin, D. M. A., Cooper, D. N., von Felten, A., Meili, E., Hann, I., Prangnell, D. R., Lumley, H., Tuddenham, E. G. D. and McVey, J. H. (1993). Detection of missense mutations by single-strand conformational polymorphism (SSCP) analysis in five dysfunctional variants of coagulation factor VII. Human Molecular Genetics 2, 1355-1359.
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84. Palmer, D. B., McVey, J. H., Robinson, P. J. and Dyson, P. J. (1992). The chromatin structure of the mouse beta-2-microglobulin locus. Differentiation 51, 201-207.
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85. Lalloz, M. R. A., McVey, J. H., Pattinson, J. K. and Tuddenham, E. G. D. (1991). Haemophilia A diagnosis by analysis of a hypervariable dinucleotide repeat within the factor VIII gene. The Lancet 338, 207-211.
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86. O'Brien, D. P., Gale, K. M. anderson, J. S., McVey, J. H., Miller, G. J., Meade, T. W. and Tuddenham, E. G. D. (1991). Purification and characterization of factor VII 304-Gln: a variant molecule with reduced activity isolated from a clinically unaffected male. Blood 78, 132-140.
    [ ABSTRACT ] [ FULL TEXT ]
87. Schwaab, R., Ludwig, M., Kochhan, L., Oldenburg, J., McVey, J. H., Egli, H., Brackmann, H. H. and Olek, K. (1991). Detection and characterisation of two missense mutations at a cleavage site in the factor VIII light chain. Thrombosis Research 61, 225-234.
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88. Crossman, D. C., Carr, D. P., Tuddenham, E. G., Pearson, J. D. and McVey, J. H. (1990). The regulation of tissue factor mRNA in human endothelial cells in response to endotoxin or phorbol ester. The Journal of Biological Chemistry 265, 9782-9787.
    [ ABSTRACT ] [ FULL TEXT ]
89. Owen, F., Poulter, M., Shah, T., Collinge, J., Lofthouse, R., Baker, H., Ridley, R., McVey, J. and Crow, T. J. (1990). An in-frame insertion in the prion protein gene in familial Creutzfeldt-Jakob disease. Molecular Brain Research 7, 273-276.
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90. Paleolog, E. M., Crossman, D. C., McVey, J. H. and Pearson, J. D. (1990). Differential regulation by cytokines of constitutive and stimulated secretion of von Willebrand factor from endothelial cells. Blood 75, 688-695.
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91. Pattinson, J. K., Millar, D. S., McVey, J. H., Grundy, C. B., Wieland, K., Mibashan, R. S., Martinowitz, U., Tan-Un, K., Vidaud, M., Goossens, M. and Goossens, M. (1990). The molecular genetic analysis of hemophilia A: a directed search strategy for the detection of point mutations in the human factor VIII gene. Blood 76, 2242-2248.
    [ ABSTRACT ] [ FULL TEXT ]
92. Pattinson, J. K., McVey, J. H., Boon, M., Ajani, A. and Tuddenham, E. G. D. (1990). CRM+ haemophilia A due to a missense mutation (372→Cys) at the internal heavy chain thrombin cleavage site. British Journal of Haematology 75, 73-77.
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93. Nomura, S., Hashmi, S., McVey, J. H., Ham, J., Parker, M. and Hogan, B. L. N. (1989). Evidence for positive and negative regulatory elements in the 5'-flanking sequence of the mouse Sparc (osteonectin) gene. The Journal of Biological Chemistry 264, 12201-12207.
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94. Graham, A., Papalopulu, N., Lorimer, J., McVey, J. H., Tuddenham, E. G. D. and Krumlauf, R. (1988). Characterization of a murine homeo box gene, Hox-2.6, related to the Drosophila Deformed gene. Genes & Development 2, 1424-1438.
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95. McVey, J. H., Nomura, S., Kelly, P., Mason, I. J. and Hogan, B. L. M. (1988). Characterization of the mouse SPARC/osteonectin gene. Intron/exon organization and an unusual promoter region. The Journal of Biological Chemistry 263, 11111-11116.
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96. Barlow, D. P., McVey, J. H. and Hogan, B. L. M. (1987). [26] Molecular cloning of laminin. Methods in Enzymology 144, 464-474.
97. Holland, P. W. H., Harper, S. J., McVey, J. H. and Hogan, B. L. M. (1987). In vivo expression of mRNA for the Ca++-binding protein SPARC (osteonectin) revealed by in situ hybridization. The Journal of Cell Biology 105, 473-482.
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98. Krumlauf, R., Holland, P. W. H., McVey, J. H. and Hogan, B. L. M. (1987). Developmental and spatial patterns of expression of the mouse homeobox gene, Hox 2. 1. Development 99, 603-617.
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99. Craig, R. K., Edbrooke, M. R., Riley, J. H., McVey, J. H. and Parker, D. (1985). Differential expression of the human calcitonin--CGRP gene in medullary thyroid carcinoma and lung carcinoma cell lines. Recent Results Cancer Research 99, 71-78.
100. Edbrooke, M. R., Parker, D., McVey, J. H., Riley, J. H., Sorenson, G. D., Pettengill, O. S. and Craig, R. K. (1985). Expression of the human calcitonin/CGRP gene in lung and thyroid carcinoma. The EMBO Journal 4, 715-724.
     [ ABSTRACT ] [ FULL TEXT ]

1. Gomez, K., Tuddenham, E. G. D. and McVey, J. H. (2009). Normal haemostasis. In Postgraduate Haematology, A. V. Hoffbrand, E. G. D. Tuddenham, and D. Catovsky, eds. Blackwell Publishing. In press.
2. Kemball-Cook, G., McVey, J. H. and Tuddenham, E. G. D. (2009). Structure, biology, and genetics of factor VIII. In Hematology: basic principles and practice, R. Hoffman, E. J. Benz, S. J. Shattil, B. Furie, L. Silberstein, P. McGlave, and H. Heslop eds. Churchill Livingstone. ISBN 9780443067150.
3. McVey, J. H. (2007). Molecular phylogeny. In Endothelial Biomedicine. ed. Aird, W. C., pp. 113-121. Cambridge: Cambridge University Press. ISBN 9780521853767.
4. McVey, J. H. (2007). Tissue factor and factor VII: initiation of blood coagulation. In Protein Epidemiology: Understanding Human Disease at the Level of Protein Structure and Function. ed. Dunn, B. Henry Stewart Talks.
   [ PRESENTATION ]
5. McVey, J. H. and Tuddenham, E. G. D. (2007). Genomics of Haemostasis. In Genomics and Clinical Medicine. ed. Kumar, D. and Weatherall, D., Oxford: Oxford University Press. ISBN 9780195188134.
6. McVey, J. H. (2006). Coagulation Factors. In Clinical Hematology. ed. Young, N. S., Gerson, S. L. and High, K. A., pp. 103-112. Philadelphia: Elsevier. ISBN 9780323019088.
7. Kemball-Cook, G., Tuddenham, E. G. D. and McVey J. H. (2005). Normal haemostasis. In Postgraduate Haematology. ed. Hoffbrand, E. V., Tuddenham, E. G. D. and Catovsky, D., pp. 783-807. Oxford: Blackwell Publishing Ltd. ISBN 9781405108218.
8. McVey, J. H. and Tuddenham, E. G. D. (2003). Hemophilia and other bleeding disorders: genetics. In Encyclopedia of the Human Genome. ed. Cooper, D. New York: Nature Publishing Group.
9. Johnson, K. M. and McVey, J. H. (1999). Molecular analysis in factor XI deficiency. In Methods in Molecular Medicine 31: Haemostasis and Thrombosis Protocols. ed. Perry, D. J. and Passi, K. J., pp. 211-221. Totowa: Humana Press Inc.
10. O'Brien, D. P. and McVey, J. H. (1993). Blood coagulation, inflammation, and defence. In The Natural Immune System: Humoral Factors. ed. Sim, E. and Kerr, M. A. Oxford: Oxford University Press.
11. McVey, J. H., Pattinson, J. K. and Tuddenham, E. G. D. (1990). Molecular biology in blood coagulation. In Recent Advances in Blood Coagulation. Poller, L. ed., pp. 79-92. Edinburgh: Churchill Livingstone.
12. Papalopulu, N., Graham, A., Lorimer, J., Kenny, R., McVey, J. and Krumlauf, R. (1987). Structure, expression and evolutionary relationships of murine homeobox genes in the HOX-2 cluster. In Cell to Cell Signals in Mammalian Development. ed. Mummery, C. L. Berlin: Springer-Verlag.
13. Hogan, B. L., Barlow, D. P., Green, N. M., Elliott, R. W., McVey, J., Patel, G., Kurkinen, M. and Cooper, A. R. (1985). Laminin: towards the structure of the protein and its genes. In The Proceedings of the International Symposium on Biology and Chemistry of Basement Membranes, Mishima, Japan, 24-26th June 1985. pp. 147-154. Amsterdam: Elsevier.